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Project: Multi-omic networks in gliomas

Acronym: MONET
Main Objective:
The MONET project will advance current research on the identification and validation of glioma networks across multiple omic layers and molecular biomarkers, aiming at improving patient diagnosis, prognosis, and therapeutic decisions, in a two-fold goal: i) identifying intertumoral multi-omics network-based differences and similarities in different glioma subtypes; and ii) assessing intratumoral heterogeneity in glioblastoma, the most heterogeneous and malignant type of brain cancer, through the identification of distinct and shared single-cell network-based profiles across glioblastoma clones, towards the development of new therapies targeting multiple clones.
Reference: PTDC/CCI-BIO/4180/2020
Funding: FCT
Start Date: 01-03-2021
End Date: 29-02-2024
Team: Alexandra Sofia Martins de Carvalho, Mario Alexandre Teles de Figueiredo
Groups: Pattern and Image Analysis – Lx
Partners: INESC-ID,, Universidade do Minho
Local Coordinator: Alexandra Sofia Martins de Carvalho

Associated Publications