The role of interference in wireless networks has recently been profoundly re-though with the emergence of news ways of combating it and actually making it to work in order to maximize the use of the physical resources. This paper presents a two-way relay channel using a lattice-based physical layer network coding, massive MIMO, and in-band full-duplex taking into account the residual self-interference that results after applying recently developed cancellation techniques of the loopback interference. The proposed scheme is able to ultimately exchange information across the TWRC in only one time slot, whereas four time slots would be needed in a conventional TWRC. The system's performance is shown to be mostly dependent on the number of antennas at the relay.